Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-09-04
1998-07-28
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544279, C07D47102, A61K 31505
Patent
active
057863580
ABSTRACT:
aromatic amides, such as a benzamide or thienylcarboxamide in which the amino portion of the amide is other than L-glutamic acid are inhibitors of enzymes which utilize folic acid, in particular glycinamide ribonucleotide formyl transferase. A typical embodiment is l)ethyl!benzoyl}-L-.gamma.-glutamyl)-D-aspartic acid.
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Gill William J.
Gossett Lynn S.
Metz James T.
Shih Chuan
Taylor Edward C.
Coleman Brenda
Shah Mukund J.
The Trustees of Princeton University
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