Pyridopyrimidine derivatives, pharmaceutical compositions contai

Details Pyridopyrimidine derivatives, pharmaceutical compositions contai Pyridopyrimidine derivatives, pharmaceutical compositions contai

1993-06-21

1995-02-07

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544282, A61K 31505, C07D47104

Patent

active

053875885

ABSTRACT:
The present invention relates to novel 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives of the general formula (I) and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) ##STR1## R stands for a C.sub.1-12 alkyl group optionally substituted by a C.sub.1-4 alkoxycarbonyl group; a C.sub.3-9 cycloalkyl, adamantyl or optionally substituted phenyl group;

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J. Chem. Soc., Perkin I., pp. 789 to 795, (1977).
Tetrahydron Letters, No. 12, pp. 1019 to 1020 (1975).
Magyar Kemikusok Lapja, 31(6), pp. 281-291 (1976)--Plus English Translation--.

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