Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1993-11-02
1995-05-30
Bernhardt, Emily
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544233, 544234, 544115, 544117, 546299, 546310, 548224, 548228, 548473, 435 71, 435 28, 436 92, 436 98, 436528, 436531, 5303913, C07D51314, C07D48704, C07D48714, G01N 33573
Patent
active
054202752
ABSTRACT:
An assay method which comprises utilizing chemiluminescence of a pyridopyridazine compound of the formula ##STR1## wherein R.sub.1 is a hydrocarbon group or a heterocyclic group each of which may be substituted and R.sub.2 is hydroxy group, thiol group, amino group or a monosubstituted amino group, and when R.sub.2 is a monosubstituted amino group, R.sub.2 may be taken together with R.sub.1 to form the ring; R.sub.3 is hydrogen atom, a hydroxy group which may be substituted, an amino group which may be substituted, a thiol group which may be substituted, a halogen atom, a heterocyclic group, nitro group, cyano group, carboxyl group which may be esterified or amidated, azido group, sulfo group or an organic sulfonyl group, provided that when R.sub.1 is an aliphalic group, R.sub.3 is not hydrogen atom; and X is oxygen atom or sulfur atom/or a salt thereof; and a novel compound of the formula (I) wherein the symbols are as defined above with proviso that R.sub.3 is hydrogen atom, R.sub.1 is a substituted aryl group or a heterocyclic group which may be substituted, or a salt thereof and the production methods thereof.
REFERENCES:
patent: 3948908 (1976-04-01), Yurugi et al.
patent: 4005201 (1977-01-01), Yurugi et al.
patent: 4010265 (1977-03-01), Yurugi et al.
patent: 4017490 (1977-04-01), Yurugi et al.
Kondrat'Eva et al, Chemical Abstracts, vol. 54, No. 12131e (1960).
Miki et al, Chemical Abstracts, vol. 73, No. 77268h (1970). (Abstract for JP 70-18458).
YakugakuZasshi, No. 6, Matsuo et al., "Synthesis of Pyrido [3,4-d]pyridazine and a-Styrylpyridazine Derivatives from Dimethyl5-Hydroxy-6-methycinchomeronat" pp. 703-707. (1972).
Chem. Pharm. Bulletin, No. 11, vol. 24, No. 76, pp. 2699-2710, Omura et al., "Studieson the Syntheses of N-Heterocyclic Compounds.XXVIII. Syntheses of Pyrido[3,4-d]pyridazine Derivatives". (1976).
Aramaki Yoshio
Masuya Hirotomo
Bernhardt Emily
Takeda Chemical Industries Ltd.
LandOfFree
Pyridopyridazine compounds and their use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyridopyridazine compounds and their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyridopyridazine compounds and their use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-363116