Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-02
2007-10-02
Tucker, Zachary C (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S350000
Reexamination Certificate
active
10851976
ABSTRACT:
The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations
REFERENCES:
patent: 5424311 (1995-06-01), Billhardt-Troughton et al.
patent: 2002/0107251 (2002-08-01), Shimazaki et al.
patent: 2005/0032803 (2005-02-01), Eckhard et al.
patent: WO99/17759 (1999-04-01), None
patent: WO 03/024448 (2003-03-01), None
patent: WO03/084473 (2003-10-01), None
patent: WO03/086394 (2003-10-01), None
patent: WO03/086403 (2003-10-01), None
patent: WO 2004/005472 (2004-01-01), None
patent: WO2004/030635 (2004-04-01), None
Gazit et al, “Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase: Structure-Activity Relationships in Quinoxalines, Quinolines and Indole Tyrphostins” Journal of Medicinal Chemistry, vol. 39(11), pp. 2170-2177 (1996).
Petrow and Saper, “Some 5-Azaquinolines and 4-Azabenzimidazoles” Journal of the Chemical Society, pp. 1389-1392 (1948).
Vippagunta et al, “Crystalline Solids” Advanced Drug Delivery Reviews, vol. 48, pp. 3-26 (2001).
Gavezzoti, A. “Are Crystal Structures Predictable?” Accounts of Chemical Research, vol. 27, pp. 309-314 (1994).
Hawley's Condensed Chemical Dictionary, 13thEdition, pp. 34 and 838, © 1997 by Van Nostrand Reinhold.
Levey, D. “The Evolutionary Ecology of Ethanol Production and Alcoholism” Integrative and Comparative Biology, vol. 44(4), pp. 284-289 (2004).
Levey, D. “The Evolutionary Ecology of Ethanol Production and Alcoholism” Integrative and Comparative Biology, vol. 44(4), pp. 284-289 (2004).
Bernstein et al, “II. Derivatives of 2,6-Diaminopyridine” Journal of the American Chemical Society, vol. 69, pp. 1151-1158, (1947).
Elliot, Robert D., et al.: The Isomeric Pyridopyrazines from the Reaction of Some Tetraaminopyridines with Pyruvaldehyde and Benzil. In: Isomeric Pyridophyrazines, vol. 33, No. 6, Jun. 1968, 2393-2397.
Temple, Carroll, Rener, Gregory A.: Potential Antimitotic Agents. Synthesis of Some Ethyl Benzopyrazin-7-ylcarbamates, Ethyl Pyrido[3,4-b]pyrazin-7-ylcarbamates, and Ethyl Pyrido[3,4-e]-as-triazin-7-ylcarbamates; J. Med. Chem. 1990, 33, 3044-3050.
Claus Eckhard
Günther Eckhard
Rapp Ulf R.
Seipelt Irene
Wixler Ludmilla
AEterna Zentaris GmbH
Goodwin-Procter LLP
Tucker Zachary C
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