Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-01-25
1997-04-01
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514810, 514811, 514812, 514813, A61K 31495, A61K 3150
Patent
active
056165854
ABSTRACT:
Racemic or optically active pyrido[1,2-a]pyrazine derivatives of the formula ##STR1## wherein X is N or CH and Y represents one of certain pyrazolo, triazolo, tetrazolo or cyclic imido radicals are useful in the treatment of abuse of and/or addiction to such substances as narcotics, alcohol and nicotine.
REFERENCES:
patent: 5122525 (1992-06-01), Bright et al.
Chemical Abstracts 114 (9): 81886r, Bright, G.M. et al. (1990).
G. D. Tollefson, British Journal of Psychiatry 159, 34-39 (1991).
C. C. Chen, Japanese Journal of Psychiatry and Neurology 46(1), 197-203 (1992).
E. D. Levin, Pharmacology Biochemistry and Behaviour 44, 51-61 (1993).
E. B. Ribeiro, Brain Research 621, 311-318 (1993).
Cintins Marianne M.
Ginsburg Paul H.
Moezie M.
Pfizer Inc.
Richardson Peter C.
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