Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-06-13
1992-10-06
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546268, 546273, 546288, C07D21385, A61K 3144
Patent
active
051532093
ABSTRACT:
Pyridones of formula (I) for treating congestive heart failure: ##STR1## wherein: R.sup.1 and R.sup.2 are a variety of phenyl substituents, L is a divalent alkylene linking group. Pharmaceutical composition, methods for their use in treating cardiovascular conditions, processes used in synthesis and intermediates used in such processes.
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patent: 4397854 (1983-08-01), Sicar
patent: 4413127 (1983-11-01), Singh
patent: 4608383 (1986-08-01), Wiedemann
Slater, R. A. et al., J. Med, Chem. 31, p. 345-351 (1988).
Curran, W. V. et al., J. Med. Chem., vol. 17, No. 3, p. 273-281 (1974).
Kenakin Terrence P.
Shaffer Joel E.
Wheeler Thomas N.
Glaxo Inc.
Joyner Charles T.
Levy David J.
Rotman Alan L.
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