Pyrido(2,3-d) pyrimidinones

Details Pyrido(2,3-d) pyrimidinones Pyrido(2,3-d) pyrimidinones

1975-06-02

1977-02-22

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602565R, 424251, C07D47104

Patent

active

040091660

ABSTRACT:
The compounds of the present invention can be represented by the following formula: ##STR1## wherein R is selected from the group consisting of phenyl and substituted phenyl; R' is selected from the group consisting of hydrogen, lower alkyl, unsaturated lower alkyl, substituted lower alkyl, lower alkoxycarbonyl and aralkyl; Y and Z are selected from the group consisting of carbonyl and methylene, but Y and Z are always dissimilar.
The compounds of the present invention possess a high degree of pharmacological activities such as anti-inflammatory, anti-ulcerative, analgetic, antipyretic, antihistaminic and central nervous system depressive activities, and certain of them are useful as new anti-inflammatory agents, analgesics and central nervous system depresssants.

REFERENCES:
patent: 3853898 (1974-12-01), Hardtmann et al.
patent: 3873545 (1975-03-01), Osselaere et al.
patent: 3922275 (1975-11-01), Noda et al.

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