Pyrido[1,2-a]pyrimidine compounds, corresponding intermediates a

Details Pyrido[1,2-a]pyrimidine compounds, corresponding intermediates a Pyrido[1,2-a]pyrimidine compounds, corresponding intermediates a

1987-04-13

1989-01-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544282, 546312, C07D47104, A61K 31505

Patent

active

047988320

ABSTRACT:
Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: ##STR1## where R is a hydrogen atom, a halogen atom or a methyl group, and n is 0, 1 or 2. The pyrido[1,2-a]pyrimidine derivatives and their salts exhibit an excellent antagonistic effect on slow-reacting substance of anaphylaxis and, therefore, are useable for the treatment of allergic diseases.

REFERENCES:
patent: 4122274 (1978-10-01), Juby
patent: 4213903 (1980-07-01), Bantick
patent: 4617407 (1986-10-01), Young
patent: 4661505 (1987-04-01), Marshall
patent: 4667055 (1987-05-01), Gillard
Morrison & Boyd, "Organic Chemistry", 2nd Ed., Allyn and Bacon, Inc., Boston (1966), pp. 562-565.

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