Pyridinylpyrazolopyrimidinone derivatives as PDE 7 inhibitors

Details Pyridinylpyrazolopyrimidinone derivatives as PDE 7 inhibitors Pyridinylpyrazolopyrimidinone derivatives as PDE 7 inhibitors

2011-05-17

2011-05-17

Moore, Susanna (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S262000

Reexamination Certificate

active

07943624

ABSTRACT:
To provide the compounds inhibiting PDE 7 selectively, and therefore, enhance cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic disease, inflammatory disease or immunologic disease. The compound is pyridinylpyrazolo-pyrimidinone compound represented by the following formula (IA) or (IB):especially, R1is cyclohexyl or cycloheptyl group, R2is methyl; R3is a group: —NR5R6or —S(O)0-2R8;hydrogen atom; nitro group; cyano group; a halogen atom; heteroaryl group; and R4is methoxy or ethoxy group.

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