Pyridinylbisphosphonates for use as a therapeutical agent

Details Pyridinylbisphosphonates for use as a therapeutical agent Pyridinylbisphosphonates for use as a therapeutical agent

1998-12-23

2000-07-04

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

546 22, 546 24, A61K 31675, C07F 958

Patent

active

060839384

ABSTRACT:
The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisophosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis.

REFERENCES:
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patent: 4973576 (1990-11-01), Sakamoto et al.
Chemical Abstracts, vol. 102(21) abst. No. 192, 195r, Nov. 19, 1984.
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Chemical Abstracts, vol. 106(12) abst. No. 90180t, Mar. 23, 1987.
Chemical Abstracts, vol. 109(25) abst. No. 222, 488y, Dec. 19, 1998.
Chemical Abstracts, vol. 117(25) abst. No. 251, 566q, Dec. 21, 1992.

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