Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-02
1999-07-13
Lambkin, Deborah C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514277, 546339, 546340, 546301, A61K 3144, C07D21172
Patent
active
059227427
ABSTRACT:
The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
REFERENCES:
patent: 5344991 (1994-09-01), Reitz et al.
patent: 5367079 (1994-11-01), Bruneau et al.
patent: 5420287 (1995-05-01), Reitz et al.
patent: 5474995 (1995-12-01), Durcharme et al.
Black Cameron
Hughes Greg
Wang Zhaoyin
Billups Richard C.
Lambkin Deborah C.
Merck Frosst Canada
Rose David L.
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