Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-06-24
1997-09-16
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21186, A61K 3144
Patent
active
056682891
ABSTRACT:
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions and have the following structure: ##STR1## for example: ##STR2##
REFERENCES:
patent: 5260307 (1993-11-01), Ackermann et al.
patent: 5405854 (1995-04-01), Ackermann et al.
Bernstein, et al., J. Med. Chem., 37, 3313-3326 "Nonpeptidic Inhibitors of Human Leukocyte Elastase . . . ", 1994.
Dorsey Bruce D.
Dyer Dona L.
Fraley Mark E.
Isaacs Richard C. A.
Naylor-Olsen Adel M.
Aulakm Charanjit S.
Ivy C. Warren
Merck & Co. , Inc.
Parr Richard S.
Winokur Melvin
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