Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-05-30
1996-10-22
Gibson, Sharon
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540224, 540225, A61K 3143, C07D50160
Patent
active
055676987
ABSTRACT:
Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl, pyridyl or benzthiazolyl group; R.sup.1 is selected from certain optionally substituted aliphatic, aromatic, arylaliphatic or sugar moieties and R.sup.2 and R.sup.3 are each independently hydrogen, alkyl or aminoalkylcarbonylamino are gram-positive antibacterial agents, especially useful in the treatment of infectious diseases caused by methicillin-resistant Staphylococcus aureus (MRSA).
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Bronson Joanne J.
D'Andrea Stanley V.
Hoeft Shelley E.
Hudyma Thomas W.
Kim Choung U.
Bristol--Myers Squibb Company
Gibson Sharon
Morse David M.
Myers, Jr. Richard S.
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