Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-03-23
1994-08-16
Dentz, Bernard
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
436518, 436536, 436547, 436822, 5303898, C07D47104, G01N 3353
Patent
active
053388500
ABSTRACT:
The present invention provides novel pyridinium derivatives which are effective, for example, in diagnosis of diabetes, diabetic complications, aging, diseases accompanied by aging, etc. and also provides an antibody prepared from said derivative as a hapten.
The pyridinium derivatives of the present invention are novel compounds represented by the following general formulae: ##STR1## wherein R and R' may be the same or different and are optionally substituted alkyl groups, and their pharmaceutically acceptable salts.
It is possible to conduct the diagnosis of diabetes, diabetic complications, aging, diseases accompanied by aging, etc. using a compound of the present invention as an indicator. Moreover, it is possible to utilize a compound of the present invention for the evaluation of the pharmaceutical effect of pharmaceuticals effective for diabetes-related diseases, aging and diseases accompanied by aging.
REFERENCES:
Nakamura et al., J. Chem. Soc., Chem. Communications, (14) pp. 992-994 (Jul. 1, 1992).
Hochi Toshikazu
Ienaga Kazuhara
Kakamura Ko
Dentz Bernard
Nippon Zoki Pharmaceutical Co. Ltd.
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