Pyridine n-oxides

Details Pyridine n-oxides Pyridine n-oxides

1977-09-09

1978-09-19

Giles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544360, 26029369, 544 60, 544 82, 544124, 4242484, 42424856, 424246, 2602433, 544364, 544357, C07D40104

Patent

active

041153960

ABSTRACT:
Some new 4-amino-2-lower-alkyl-6-variable-pyridine-1-oxides are described. A new process is provided. The 6-variable is lower-alkyl, amino or substituted amino including saturated heterocyclic amino, e.g., pyrrolidinyl, piperidino, etc. The compounds are hypotensive agents and reduce blood pressure in animals.

REFERENCES:
patent: 4067874 (1978-01-01), Ursprung
Ochiai, "J. Org. Chem.", 18 pages, 534-551, (1953).
Culvenor, "Amine Oxides", Rev. Pure and Applied Chem., vol. 3, pp. 83-114, (1953).
Anker et al., "J. Chem. Soc.", (1946), pp. 117-120.

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