Pyridine carboxamide orexin receptor antagonists

Details Pyridine carboxamide orexin receptor antagonists Pyridine carboxamide orexin receptor antagonists

2011-08-23

2011-08-23

Andres, Janet (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S262000

Reexamination Certificate

active

08003797

ABSTRACT:
The present invention is directed to pyridyl carboxamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

REFERENCES:
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patent: 2009/0088452 (2009-04-01), Coleman et al.
patent: 2010/0035931 (2010-02-01), Coleman et al.
patent: 2010/0063056 (2010-03-01), Coleman et al.
patent: WO2007/061763 (2007-05-01), None
patent: WO2008/108991 (2008-09-01), None
patent: WO2010051236 (2010-05-01), None
Silverman, R. “The Organic Chemistry of Drug Design and Drug Action,” 2004, Elsevier, pp. 29-32.

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