Pyridine analogs as C5a antagonists

Details Pyridine analogs as C5a antagonists Pyridine analogs as C5a antagonists

2008-09-30

2008-09-30

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S311000, C514S314000

Reexamination Certificate

active

11053623

ABSTRACT:
The present invention provides novel compounds of Formula I which are antagonists of the C5a receptor. Compounds of the present invention are useful for the treatment of various C5a-mediated diseases and disorders; accordingly the present invention provides a method for the treatment of C5a-mediated diseases using the novel compounds described herein, as well as pharmaceutical compositions containing them.

REFERENCES:
patent: 318 140 (2003-06-01), None
patent: WO 03/082826 (2003-10-01), None
patent: WO 03/082828 (2003-10-01), None
The Journal Of Biological Chem., vol. 277, No. 51, Issue of Dec. 20, pp. 49403-49407, 2002.

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