Pyridazinyl-ergoline compounds having neuroleptic activity

Details Pyridazinyl-ergoline compounds having neuroleptic activity Pyridazinyl-ergoline compounds having neuroleptic activity

1978-01-17

1979-09-04

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

546 67, 424250, C07D45702, A61K 3150

Patent

active

041669118

ABSTRACT:
Pyridazinyl-ergoline compounds having neuroleptic activity are obtained by reacting an 8.beta.-tosylmethyl ergoline with the sodium derivative of an amino-pyridazine or a mercaptopyridazine in a dipolar aprotic solvent.

REFERENCES:
patent: 3598822 (1971-08-01), Anderson et al.
patent: 3642792 (1972-02-01), Bellasio
patent: 3687971 (1972-08-01), Shen et al.
patent: 3856799 (1974-12-01), Hoehn et al.
patent: 3891641 (1975-06-01), Pifferi
patent: 3957785 (1976-05-01), Arcari et al.
patent: 3957805 (1976-05-01), Fanshawe et al.
patent: 3975388 (1976-08-01), Hakim et al.

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