Pyridazinone derivatives and salts thereof as cardiac stimulants

Details Pyridazinone derivatives and salts thereof as cardiac stimulants Pyridazinone derivatives and salts thereof as cardiac stimulants

1984-12-06

1987-04-28

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514242, 514245, 514248, 514252, 544182, 544198, 544209, 544212, 544237, 544238, 544235, C07D40112, C07D40312, A61K 3150, A61K 3153

Patent

active

046614842

ABSTRACT:
There are provided novel pyridazinone derivatives having the general formula (I): ##STR1## wherein A represents 5- or 6-membered heterocyclic ring having 1-3 nitrogen atoms, which may be substituted by at least one member selected from the group consisting of C.sub.1-5 alkyl, cyano, hydroxyl, C.sub.1-5 alkoxy, amino, C.sub.1-5 alkylamino, C.sub.2-6 dialkylamino, C.sub.2-5 acylamino, carboxyl, C.sub.2-5 alkoxycarbonyl and carbamoyl, and R.sup.1 and R.sup.2 independently represent hydrogen atom or C.sub.1-5 alkyl or R.sup.1 and R.sup.2 may form together C.sub.1-5 alkylene, and salts thereof.

REFERENCES:
patent: 4353905 (1982-10-01), Sircar et al.
patent: 4397854 (1983-08-01), Sircar
patent: 4508721 (1985-04-01), Hargreaves
patent: 4521415 (1985-06-01), Katakami
patent: 4521416 (1985-06-01), Sircar et al.
Steck et al, J. Het. Chem 11, (5), 755 (1974).

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