Pyridazinone derivatives

Details Pyridazinone derivatives Pyridazinone derivatives

1997-09-24

1999-01-05

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544238, A61K 3150

Patent

active

058563270

ABSTRACT:
Pyridazinone derivatives represented by the formula (I) and antiplatelet agents containing them: ##STR1## hydrogen atom, a chlorine atom or a bromine atom, Ar is a pyridyl group or a phenyl group substituted with OR.sup.1 (wherein R.sup.1 is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group) and A {wherein A is a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group or OR.sup.2 (wherein R.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group)}, Y is C.sub.1 -C.sub.8 alkylene wherein one carbon atom on the straight chain is substituted with one OR.sup.1 group (wherein R.sup.1 is the same as defined above), and Z.sup.1 and Z.sup.2 are independently a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group or a OR.sup.1 group (wherein R.sup.1 is the same as defined above)!. These compounds have strong antiplatelet effects, are excellently safe, and can be used as active ingredients of prophylactic and therapeutic drugs for various thrombotic diseases.

REFERENCES:
patent: 4783462 (1988-11-01), Mutsukado et al.
patent: 4892947 (1990-01-01), Mutsukado et al.
patent: 4978665 (1990-12-01), Tanikawa et al.
patent: 5011839 (1991-04-01), Tanikawa et al.
patent: 5098900 (1992-03-01), Matsukado et al.
patent: 5202323 (1993-04-01), Tanikawa et al.
patent: 5219854 (1993-06-01), Nakashima et al.
patent: 5314883 (1994-05-01), Tanikawa et al.
patent: 5318968 (1994-06-01), Tanikawa et al.
patent: 5728702 (1998-03-01), Tanikawa et al.
patent: 5763439 (1998-06-01), Shigehara

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