Pyridazinone compounds

Details Pyridazinone compounds Pyridazinone compounds

2005-12-16

2008-09-16

Habte, Kahsay T (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S010000, C544S012000, C514S223200

Reexamination Certificate

active

07425552

ABSTRACT:
The invention is directed to pyridazinone compounds of Formula I and pharmaceutical compositions containing compounds of Formula Iwherein R1and R2are independently H, alkyl, cycloalkyl, aryl, or heterocyclyl; and Ring A is 5 or 6-membered aryl or heterocyclyl. The invention also encompasses methods of using a compound of Formula I in the treatment of hepatitis C virus infections.

REFERENCES:
patent: 2005/0153877 (2005-07-01), Miao et al.
patent: 2006/0003346 (2006-01-01), Amin et al.
patent: 2006/0040927 (2006-02-01), Blake et al.
patent: 2006/0189602 (2006-08-01), Zhou et al.
patent: 2006/0211695 (2006-09-01), Borzilleri et al.
patent: 2006/0252785 (2006-11-01), Blake et al.
patent: 2008/0031852 (2008-02-01), Webber et al.
patent: WO 01/85172 (2001-11-01), None
patent: WO 2002/098424 (2002-12-01), None
patent: WO 03/059356 (2003-07-01), None
patent: WO-2006/115221 (2006-11-01), None
Int'l Search Report and Written Opinion of Int'l Appl. No. PCT/US05/45588.
U.S. Appl. No. 11/766,668, Ellis et al.
U.S. Appl. No. 11/898,334, Zhou et al.
U.S. Appl. No. 11/861,678, Dragovich et al.
U.S. Appl. No. 11/955,193, Ruebsam et al.
U.S. Appl. No. 11/955,144, Tran et al.
U.S. Appl. No. 12/048,933, Ruebsam et al.
U.S. Appl. No. 12/061,499, Ellis et al.
U.S. Appl. No. 11/845,515, Tran et al.
Tedesco et al., 3-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, J. Med. Chem. 49:971-983 (2006).
Fisyuk et al., Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydrosoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction. Molecules, Feb. 28, 2002, vol. 7, pp. 124-128.
Int'l Search Report and Written Opinion of Int'l Appl. No. PCT/US07/87272.
Intl'l Search Report and Written Opinion of Int'l Appl. No. PCT/US07/87288.

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