Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-04-24
1997-02-04
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544 94, 544285, 544234, 546123, 546156, 546159, 546170, 546318, 548485, 558414, 560 22, 560 29, 560 30, 560 47, 562434, 562458, 564194, 564442, 568937, A61K 3150, C07D47104, C07D47114
Patent
active
055998143
ABSTRACT:
The present invention relates to pyridazino[4,5-b]quinolines, and pharmaceutically useful salts thereof, which are excitatory amino acid antagonists and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides pharmaceutical compositions containing pyridazino[4,5-b]quinolines as active ingredient, and methods for the treatment of neurological disorders.
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Lou et al., "The Synthesis of Two Novel Fused Thienopyridopyridazines [1]" J. Heterocyclic Chem., (1991), 28, 205-208.
Godard et al., "Syntheses et proprietes de quelques derives de la pyridazino[4,5-b]quinoleine" Bulletin de la Societe Chimique de France (1972) No. 4, 1588-1592.
Kurasawa et al., "A Convenient Synthesis of Pyridazino[4,5-b]quinolines and Pyrrolo[3,4-b]quinolines" Chemical & Pharmaceutical Bulletin (1980) No. 12, 3457-3465.
Bare Thomas M.
Sparks Richard B.
Alexander Michael D.
Bernhardt Emily
Imperial Chemical Industries PLC
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