Pyridazine compounds, their production and use

Details Pyridazine compounds, their production and use Pyridazine compounds, their production and use

1992-12-28

1994-11-29

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142325, 5142342, 514248, 540599, 544115, 544116, 544117, 544234, 544236, 558 15, 558452, 560150, 564 95, 564 96, A61K 3150, A61K 3155, C07D48704, C07D48714

Patent

active

053691040

ABSTRACT:
Novel compound represented by the formula: ##STR1## wherein X stands for a methine (i.e. the group --CH.dbd.) group or a nitrogen atom; R.sup.1 stands for a hydrogen atom, an optionally substituted lower alkyl group or a halogen atom; R.sup.2 and R.sup.3 respectively stand for a hydrogen atom or an optionally substituted lower alkyl group, or, taken together, may form a 5- to 7-membered ring combined with the adjacent --C.dbd.C--; R.sup.4 and R.sup.5 respectively stands for a hydrogen atom or an optionally substituted lower alkyl group or, taken together, form a 3- to 7-membered homo- or heterocyclic ring combined with the adjacent carbon atom; A stands for an optionally substituted amino group; m and n denote 1 to 4, respectively, or salts thereof which has an antiallergic, antiinflammatory and anti-PAF activity and is useful as an antiasthmatic agent.

REFERENCES:
patent: 5145850 (1992-09-01), Miyake et al.
patent: 5155108 (1992-10-01), Miyake et al.
patent: 5202324 (1993-04-01), Miyake et al.

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