Pyridazine and pyrimidine compounds active on the central nervou

Details Pyridazine and pyrimidine compounds active on the central nervou Pyridazine and pyrimidine compounds active on the central nervou

1984-01-16

1986-11-25

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544224, 544230, 544238, 544332, 514247, 514275, C07D40104, C07D23720, A61K 31445, A61K 3150

Patent

active

046249524

ABSTRACT:
The present invention relates to the compounds of formula ##STR1## in which X.sub.1 represents N or ##STR2## X.sub.2 represents N or ##STR3## provided that X.sub.1 and X.sub.2 are different from each other; R.sub.1 and R.sub.2 being --(CH.sub.2).sub.n OH wherein n is 1 to 4 or ##STR4## represents a saturated heterocycle with 5 or 6 groupings containing one nitrogen atom as heteroatom, substituted in 3 or 4 position for example by (CH.sub.2).sub.m OR.sub.6 where R.sub.6 is H or an acyl radical or an amido radical; to a process for preparing said compounds; and to the drugs containing said compounds active in particular on the central nervous system.

REFERENCES:
patent: 4169158 (1979-09-01), Laborit
patent: 4302455 (1981-11-01), Huff et al.

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