Pyrazolyl amino imidazolines as diuretic agents

Details Pyrazolyl amino imidazolines as diuretic agents Pyrazolyl amino imidazolines as diuretic agents

1979-05-07

1980-10-07

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424256, 424258, 424263, 424274, A61K 3140, A61K 3147, A61K 31415, A61K 31435

Patent

active

042267730

ABSTRACT:
Described is a method of increasing urinary excretion by administering effective amounts to a subject in need thereof of compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, loweralkyl, lowercycloalkyl, aralkyl, aryl, pyridyl, isoquinolyl or phthalazinyl, or aryl substituted by one or more hydrogen, halo, loweralkyl, lowercycloalkyl, haloloweralkyl, aminosulfonyl, nitro, hydroxy, alkoxy, carboxy, alkoxycarbonyl, cycloalkoxy carbonyl, aminocarbonyl, diloweralkylaminocarbonyl or ##STR2## wherein n is 4 or 5.

REFERENCES:
patent: 3113949 (1963-12-01), Bicking
patent: 4108982 (1978-08-01), Amschler
patent: 4171367 (1979-10-01), Winn et al.
Chem. Abst., 86, 29813(d) (1977), Trani.
Chem. Abst., 86, 140052(u) (1977), Cohnen.

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