Pyrazolopyridine derivatives as inhibitors of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S120000

Reexamination Certificate

active

07910602

ABSTRACT:
The invention relates to 6-amido substituted pyrazolopyridine derivatives of the formula (I)useful as inhibitors of beta-adrenergic receptor kinase 1 (βARK-1), compositions containing such compounds and their use for the treatment and prevention of chronic heart failure, hypertension, myocardial ischemia and hepatitis C virus (HCV) infections, and for the prevention of opiate addiction.

REFERENCES:
patent: 99-30710 (1999-06-01), None
patent: WO 03-068773 (2003-08-01), None
patent: WO 2004-014910 (2004-02-01), None
patent: WO 2004-076450 (2004-09-01), None
Tomaszewski et al., Hypertension, (Nov. 2004) vol. 44, No. 5, pp. 689-694.
Lynch, Pyrazolo[3,4-b]pyridines: syntheses, eractions, and nuclear magnetic resonance spectra, Can. J. of Chem.; 1988; 66(3); p. 426.

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