Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-06-25
1987-02-24
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546119, C07D49122, C07D47114
Patent
active
046458387
ABSTRACT:
Compounds of the formula (I): ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.7 and R.sup.8 are as described herein, D is oxygen, n is 1 or 2 and the physiologically acceptable salts thereof useful in reducing anxiety in an animal such as man. The compounds are potent anxiolytics having reduced side effects compared to known anxiolytics. Also pharmaceutical compositions, intermediates and methods of treatment and synthesis are described.
REFERENCES:
patent: 3850940 (1974-11-01), Denzel et al.
Bare Thomas M.
Heald Anthony F.
ICI Americas Inc.
Jiles Henry R.
Miano Rosemary M.
Richter J.
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