Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-25
2000-01-04
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483714, 5483717, 5483721, A61K 31415, C07D23106, C07D23114, C07D23116
Patent
active
06011052&
ABSTRACT:
Pyrazolone derivatives of Formula I or a pharmaceutically acceptable salt thereof are MCP-1 antagonists and are thus useful in the treatment of inflammatory diseases or conditions, atherosclerosis, restenosis, and immune disorders such as arthritis and transplant rejection ##STR1## where: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 can be independently H,
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Padia Janak Khimchand
Roth Bruce David
Strode John Edward
Trivedi Bharat Kalidas
Anderson Elizabeth M.
Rotman Alan L.
Warner-Lambert & Company
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