Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-12-07
1990-10-16
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 82, A61K 3147, C07D48904
Patent
active
049635581
ABSTRACT:
Pharmaceutical compounds of the formula ##STR1## in which R.sup.1 is hydrogen or C.sub.1-6 alkyl, R.sup.2 is hydrogen, C.sub.1-6 alkyl optionally substituted by C.sub.3-9 cycloalkyl or optionally substituted phenyl, C.sub.3-9 cycloalkyl, optionally substituted phenyl, or --SR.sup.4 where R.sup.4 is C.sub.1-6 alkyl optionally substituted by C.sub.3-9 cycloalkyl or optionally substituted phenyl, or C.sub.3-9 cycloalkyl, R.sup.3 is hydrogen, C.sub.1-6 alkyl optionally substituted by C.sub.3-9 cycloalkyl or optionally substituted phenyl, c.sub.3-9 cycloalkyl, or optionally phenyl, and either X and Y are both hydrogen or together are .dbd.O; and acid addition salts thereof. These compounds show useful effects on the central nervous system.
REFERENCES:
patent: 4230861 (1980-10-01), Kornfeld et al.
patent: 4468401 (1984-08-01), Hahn
patent: 4596871 (1986-06-01), Schaus et al.
patent: 4762843 (1988-08-01), Caprathe et al.
Hotten Terrence M.
Timms Graham H.
Tupper David E.
Conrad Robert A.
Lee Mary C.
Lilly Industries Limited
Mittenberger L. A.
Whitaker Leroy
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