Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections

Details Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections

2007-10-23

2007-10-23

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S263100, C544S262000, C544S264000, C544S265000, C548S100000, C548S125000

Reexamination Certificate

active

10481178

ABSTRACT:
Compounds having the general formulaand pharmaceutical compositions containing them, and their use in the treatment or prophylaxis ofH. pyloriinfection.

REFERENCES:
patent: WO 9006116 (1990-06-01), None
Fumio et al., “Synthesis of Pyrazolo[3,4-d]pyrimidines by Intramolecular cycloaddition of azahexatrienes”, J.C.S. Perkin I, (1977), 7, pp. 765-767.
Fumio Yoneda et al., “Synthesis of pyrazolo(3,4-d)pyrimidines by intramolecular cycloaddition of azahexatrienes” STN International, file CAPLUS, CAPLUS accession No. 1977:468272, Document No. 87:68272; & J. Chem. Soc., Perkin Trans.1 (1977), (7), 765-7.
Gunther Schimpl et al.; “Allopurinol Reduces Bacterial Translocation, Intestinal Mucosal Lipid Peroxidation, and Neutrophil-Derived Myeloperoxidase Activity in Chronic Portal Hypertensive and Common Bile Duct-Ligated Growing Rats”, Pediatric Research, vol. 40, No. 3, 1996, p. 422-428.
George L. Mendz et al., “Purine Metabolism and the Microaerophily of Helicobacter Pylori”, Arch Microbiol, vol. 168, 1997, p. 448-456.
Vikram S. Patel et al., “Allopurinol absorption from differenct sites of the rat gastrointestinal tract”, STN International, file CAPLUS, CAPLUS accession No. 1986:179711, Document No. 104:179711; & J. Pharm. Sci. (1986, 75(3), 275-7.

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