Pyrazolo (3,4-d) pyrimidines and methods of making

Details Pyrazolo (3,4-d) pyrimidines and methods of making Pyrazolo (3,4-d) pyrimidines and methods of making

1979-09-17

1981-04-07

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Pteroyl per se or having -c-, wherein x is chalcogen, bonded...

424251, 544256, 544236, 544279, 544320, 544321, 2602433, C07D48704, A61K 31505

Patent

active

042607582

ABSTRACT:
Novel compounds of the general formula (XIX) ##STR1## where R.sup.9 is selected from lower alkyl, phenyl, phenyl substituted by one or more hydroxy or lower alkoxy, or pyridyl, are disclosed.
A method of making the compounds of Formula (XIX) is disclosed, which comprises heating in aqueous acid a compound of formula (XX) ##STR2## wherein R.sup.10 is selected from lower alkyl, phenyl, phenyl substituted by one or more hyroxy or lower alkoxy or pyridyl and R.sup.11 is selected from lower alkyl, phenyl, substituted by one or more hydroxy or lower alkoxy, pyridyl or --CO.sub.2 R where R is lower alkyl.

REFERENCES:
patent: 3098075 (1963-07-01), Druey et al.
patent: 3165520 (1965-01-01), Schmidt et al.
patent: 3947442 (1976-03-01), Beckwith
Hauser, et al., "J. Org. Chem.", vol. 26, 1961, pp. 451-455.

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