Pyrazolo [3,4-d] pyrimidine derivatives and their use as...

Details Pyrazolo [3,4-d] pyrimidine derivatives and their use as... Pyrazolo [3,4-d] pyrimidine derivatives and their use as...

2006-01-12

2009-12-08

Moore, Susanna (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S262000

Reexamination Certificate

active

07629349

ABSTRACT:
Pharmaceutical compositions and their uses comprising compounds of formula (I):wherein: R1is selected from: alkyl, alkoxy, aryloxy, alkylthio, arylthio, aryl, halogen, CN, NR6R7, NR5COR6, NR5CONR6R7, NR5CO2R8, and NR5SO2R8; R2is a heteroaryl attached via an unsaturated ring carbon of said heteroaryl group; R3is selected from: H, alkyl, halogen, OR5, SR5, and NR6R7; R4is selected from: H, acyclic alkyl, CONR6R7, CONR5NR6R7, COR6, CO2R8, and SO2R8; R5, R6, and R7are independently selected from: H, alkyl, and aryl, or where R6and R7are in an NR6R7group, R6and R7may be linked to form a hetero cyclic group, or where R5, R6and R7are in a (CONR5NR6R7) group, R5and R6may be linked to form a heterocyclic group; and R8is selected from alkyl and aryl, or a pharmaceutically acceptable salt thereof.

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