Pyrazolo[3,4-b]quinolines and their use as antiviral agents

Details Pyrazolo[3,4-b]quinolines and their use as antiviral agents Pyrazolo[3,4-b]quinolines and their use as antiviral agents

1988-05-20

1990-04-24

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142328, 514934, 544126, 546 82, A61K 31415, A61K 31435, C07D41300, C07D47100

Patent

active

049201280

ABSTRACT:
Pyrazolo[3,4-b]quinolines having the formula ##STR1## where R is hydrogen, hydroxy or alkoxy; R.sub.2 is halogen, cyano, carbamyl, carboxy, lower-alkylcarbonyl, amino or aminomethyl; and R.sub.1 is hydrogen or selected substituents as defined herein, are useful as antiviral agents and/or as vasodilators.

REFERENCES:
Chem. Abstracts, Radl et al., vol. 106; 18429p, No. 106; 845446y (1987).
Chem. Abstracts, Radl et al., vol. 105; 226434t, No. 25 (1986).
Chem. Abstracts, Radl et al., vol. 104, No. 13; 109528v (1986).
Yoshida et al., Yakugaku Zasshi, 96, 33-6 (1976); Chemical Abstracts, 84: 121754s.
Holla et al., Bull. Chem. Soc. Japan, 57, 2984-6 (1984).
Neelima et al., J. Heterocyclic Chem., 23, 925-928 (1986).

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