Pyrazolo[1,5-a]pyridine derivatives and their use as...

Details Pyrazolo[1,5-a]pyridine derivatives and their use as... Pyrazolo[1,5-a]pyridine derivatives and their use as...

2006-12-19

2006-12-19

Owens, Amelia A. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S121000

Reexamination Certificate

active

07151109

ABSTRACT:
The present invention relates to novel pyrazolo[1,5-a]pyridine derivatives of general formula I:that bind with high affifnity to CRF1receptors, including human CRF1receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.

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