Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-06-15
1989-06-13
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514255, 514333, 544405, 544406, 546256, 546279, 548379, A61K 3702, A61K 3151, A01N 4378, A01N 3500
Patent
active
048393762
ABSTRACT:
2-Pyrazoline derivatives of the formula (A): ##STR1## where R.sup.1 is a pyridyl, a pyrazyl or an alkoxy group; and R.sup.2 is a hydrogen atom, an alkyl, a pyridyl, a furyl, phenyl or a substituted phenyl group, and to a process for producing the same. Therapeutic agents for treating cerebrovascular diseases containing, as the active ingredient, a 2-pyrazoline derivative represented by the formula (G): ##STR2## where R.sup.3 is a hydrogen atom, an alkyl, acetyl, an alkoxycarbonyl, an amino, benzoyl, a substituted benzoyl, a pyridylcarbonyl, a furylcarbonyl, a thienylcarbonyl, a pyrazylcarbonyl, an N-substituted carbamoyl, an N-substituted thiocarbamoyl, or carboxy group; and R.sup.4 is a hydrogen atom, an alkyl, a pyridyl, a thienyl, a furyl, cyclohexyl, phenyl or a substituted phenyl group or a pharmaceutically acceptable salt thereof. These therapeutic agents cope with cerebral edemas in the acute stage of cerebral apoplexy and regulates the whole-body and intracranial body circulation, thereby protecting ischemic lesions and minimizing the spread to affected parts.
REFERENCES:
patent: 4003889 (1977-01-01), Bolton et al.
patent: 4250185 (1981-02-01), Gaughan
patent: 4677210 (1987-06-01), Huang
patent: 4780543 (1988-10-01), Gordon et al.
Iizuka Hajime
Kawazura Hiroshi
Namekawa Hiroshi
Odate Makoto
Shiga Yoshio
Azpuru C.
Kight John
Mitsui Toatsu Chemicals Inc.
LandOfFree
Pyrazoline derivatives for treating cerebrovascular diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyrazoline derivatives for treating cerebrovascular diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazoline derivatives for treating cerebrovascular diseases will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1277974