Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-11-01
2009-06-02
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S326000, C546S125000, C546S208000
Reexamination Certificate
active
07541368
ABSTRACT:
The present invention provides compounds of Formula (I)and ester prodrugs, pharmaceutically acceptable salts or solvates of such compounds; or ester prodrugs of such salts or solvates; pharmaceutical compositions comprising such compounds, their preparation, and their pharmaceutical use in the treatment of disease states capable of being modulated by the inhibition of p38 kinase and/or tumor necrosis factor (TNF).
REFERENCES:
patent: WO9932110 (1999-07-01), None
patent: WO0043384 (2000-07-01), None
Dermer (Bio/Technology, 1994, 12:320).
Freshney (Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p. 4).
Dumas et al., Bioorganic & Medicinal Chemistry Letters (2002), 12(12), 1559-1562.
U.S. Appl. No. 09/909,966, filed Jul. 19, 2001, Goldstein, et al.
Borcherding David Roger
Freed Brian S.
Gross Alexandre
Shum Patrick W.
Willard Nicole
Aventis Pharmaceuticals Inc.
Bolcsak James W.
Rahmani Niloofar
Seaman D. Margaret
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