Pyrazoles and pyrazolopyrimidines having CRF antagonistic activi

Details Pyrazoles and pyrazolopyrimidines having CRF antagonistic activi Pyrazoles and pyrazolopyrimidines having CRF antagonistic activi

1997-10-30

2000-08-15

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Pteroyl per se or having -c-, wherein x is chalcogen, bonded...

C07D48704

Patent

active

061039004

ABSTRACT:
The pyrazoles and pyzazolopyrimidines of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and A are as defined herein, have corticotropin releasing factor (CRF) antagonist activity. As such, they are effective in the treatment of a wide range of diseases including stress-related illnesses.

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