Pyrazoles active in the central nervous system

Details Pyrazoles active in the central nervous system Pyrazoles active in the central nervous system

1979-05-14

1980-10-07

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548364, 548374, A61K 31415, C07D40312

Patent

active

042268770

ABSTRACT:
Disclosed are pyrazoles of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, or phenyl, R.sub.2 is hydrogen or lower alkyl, R.sub.3 is alkoxy or hydroxy, R.sub.4 is lower alkyl, and the pharmaceutically acceptable acid addition salts thereof. The compounds are useful primarily as antipsychotic agents. As an example, they exhibit central nervous system activity as antischizophrenic agents.

REFERENCES:
patent: 3875128 (1975-04-01), Bretschneider et al.
patent: 3953467 (1976-04-01), Fujimura et al.
patent: 4069330 (1978-01-01), Berger et al.

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