Pyrazole derivatives as p38 kinase inhibitors

Details Pyrazole derivatives as p38 kinase inhibitors Pyrazole derivatives as p38 kinase inhibitors

1998-05-22

2000-07-11

Stockton, Laura L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 544364, 5462761, A61K 314439, A61K 31497, C07D40104, C07D40114

Patent

active

060873817

ABSTRACT:
A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula I ##STR1## wherein Q, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as described in the specification.

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