Pyrazole derivatives and diabetic medicine containing them

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Details

C514S406000, C514S407000, C514S866000, C536S004100, C536S017400, C548S373100

Reexamination Certificate

active

11255937

ABSTRACT:
The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine

REFERENCES:
patent: 5264451 (1993-11-01), Kees
patent: 5274111 (1993-12-01), Kees
patent: 6815428 (2004-11-01), Ohsumi et al.
patent: 6908905 (2005-06-01), Ohsumi et al.
patent: 2005/0043249 (2005-02-01), Ohsumi et al.
patent: 0 850 948 (1998-07-01), None
patent: 1 213 296 (2002-06-01), None
patent: WO 01/16147 (2001-03-01), None
patent: WO 02/053573 (2002-07-01), None
patent: WO 02/068439 (2002-09-01), None
patent: WO 02/088157 (2002-11-01), None
Kenneth L. Kees et al, “New Potent Antihyperglycemic Agents in db/db Mice: Synthesis and Structure-Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones”,J. Med. Chem., 1996, 39, pp. 3920-3928.
Kenji Tsujihara et al, “Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Substituted on the B Ring”,J. Med. Chem., 1999, 42, pp. 5311-5324.

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