Pyrazole derivatives and diabetic medicine containing them

Details Pyrazole derivatives and diabetic medicine containing them Pyrazole derivatives and diabetic medicine containing them

2006-03-21

2006-03-21

Barts, Samuel (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S406000, C514S407000, C514S866000, C536S004100, C536S017400, C548S373100

Reexamination Certificate

active

07015201

ABSTRACT:
The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.

REFERENCES:
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patent: 5274111 (1993-12-01), Kees
patent: 6815428 (2004-11-01), Ohsumi et al.
patent: 2004/0110936 (2004-06-01), Ohsumi et al.
patent: 0 850 948 (1998-07-01), None
patent: WO 01/16147 (2001-03-01), None
patent: WO 02/053573 (2002-07-01), None
patent: WO 02/068439 (2002-09-01), None
patent: WO 02/088157 (2002-11-01), None
Kenneth L. Kees,et al., “New Potent Antihyperglycemic Agents in db/db Mice: Sythesis and Structure—Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pryazoles and -pryazolones,” J. Med. Chem., 1996, 39, 3920-3928.
Kenji Tsujihara, et al., “Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Substituted on the B Ring,” J. Med. Chem., 1999, 42, 5311-5324.

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