Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2004-06-15
2009-08-18
McIntosh, III, Traviss C (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S025000, C514S866000, C536S004100, C536S018100
Reexamination Certificate
active
07576064
ABSTRACT:
The present invention provides pyrazole derivatives represented by the general formula:wherein R1represents H, an optionally substituted C1-6alkyl, etc.; one of Q and T represents a group selected from the following:and the other represents -Z-Ar wherein Z represents —O—, —S—, etc.; Ar represents an optionally substituted C6-10aryl, etc.;R represents an optionally substituted C3-8cycloalkyl, an optionally substituted C6-10aryl, etc., pharmaceutically acceptable salts thereof, and prodrugs thereof, which exhibit an excellent inhibitory activity in human sodium/glucose cotransporter (SGLT) and are useful as agents for the prevention, inhibition of progression or treatment of a disease associated with the excess uptake of at least a kind of carbohydrates selected from glucose, fructose and mannose (diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, etc.), and pharmaceutical compositions containing the same, medicinal uses thereof and intermediates for production therefor.
REFERENCES:
patent: 4526895 (1985-07-01), Jarreau et al.
patent: 2002/0052326 (2002-05-01), Mathias et al.
patent: 2004/0006025 (2004-01-01), Ohsumi et al.
patent: 2004/0063646 (2004-04-01), Fujikura et al.
patent: 2004/0110936 (2004-06-01), Ohsumi et al.
patent: 2004/0116357 (2004-06-01), Fushimi et al.
patent: 2004/0176308 (2004-09-01), Shiohara et al.
patent: 1568380 (2005-08-01), None
patent: WO 02/088157 (2002-11-01), None
patent: WO 02/098893 (2002-12-01), None
patent: WO2004/050122 (2004-06-01), None
Fujikura Hideki
Isaji Masayuki
Kikuchi Norihiko
Tazawa Shigeki
Yamato Tokuhisa
Kissei Pharmaceutical Co. Ltd.
McIntosh, III Traviss C
Sughrue & Mion, PLLC
LandOfFree
Pyrazole derivative, drug composition containing the same... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyrazole derivative, drug composition containing the same..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazole derivative, drug composition containing the same... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4131393