Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2001-12-19
2009-12-01
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S324000
Reexamination Certificate
active
07625913
ABSTRACT:
This invention describes novel pyrazole compounds of formula IIIc:wherein R1is T—Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx, Ry, R2, and R2′are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
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Bebbington David
Charrier Jean-Damien
Golec Julian
Knegtel Ronald
Miller Andrew
Chung H. Joon
Rao Deepak
Vertex Pharmaceuticals Incorporated
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