Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-04-23
2009-12-15
Shiao, Rei-Tsang (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S374100
Reexamination Certificate
active
07632855
ABSTRACT:
Compounds of formula (I) are inhibitors of HSP90 activity, and useful in the treatment of proliferative disease such as cancers: wherein R1, R2and R3are as defined in the specification, and X is —OR4or —NR4R5wherein R4and R5independently represent hydrogen or optionally substituted C1-C6alkyl, or R4and R5taken together with the nitrogen to which they are attached form an optionally substituted nitrogen-containing ring having 5-8 ring atoms.
REFERENCES:
patent: WO 02/36075 (2002-05-01), None
patent: WO 03/055860 (2003-07-01), None
patent: WO 03/055860 (2003-07-01), None
Barrilalonso Xavier
Drysdale Martin James
Dymock Brian William
Banner & Witcoff , Ltd.
Cancer Research Technology
Coppins Janet L
Shiao Rei-Tsang
The Institute of Cancer
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