Pyrazole compounds as anti-inflammatory and analgesic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S375100

Reexamination Certificate

active

07001917

ABSTRACT:
This invention provides a compound of the formula (I):wherein:R1represents a hydrogen atom, an alkyl group, etc.; R2represents a hydrogen atom, a halogen atom, etc.; R3represents an alkyl group, etc.; R4represents an aryl group, etc.;A represents an aryl1, etc; B represents an alkylene etc.; X represents NH, etc.;or a pharmaceutically acceptable ester of such compound,and pharmaceutically acceptable salts thereof.These compounds are useful for the treatment of medical conditions mediated by prostaglandin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.

REFERENCES:
patent: WO 00/64888 (1998-12-01), None
patent: WO 99/19300 (1999-04-01), None
patent: WO 99/47497 (1999-09-01), None
patent: WO 98/56377 (2000-11-01), None
patent: WO 02/32900 (2002-04-01), None

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