Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-10-30
1992-01-21
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544238, 544408, C07D45302, A61K 3146
Patent
active
050828436
ABSTRACT:
Novel ethers of formula ##STR1## their heteroaromatic N-oxides, and the pharmaceutically acceptable acid additions of the compounds of formula (I) and their N-oxides possess 5-HT.sub.3 -antagonistic activity. In the formula ##STR2## represents an optionally substituted heteroaryl group containing a hetero atom X and -B represents a saturated azabicyclic ring such as quinuclidyl or tropanyl.
REFERENCES:
patent: 2640829 (1953-06-01), Wilson et al.
patent: 3716544 (1973-02-01), Gadient
patent: 4533498 (1985-08-01), Blaney et al.
patent: 4643995 (1987-02-01), Engel et al.
patent: 4766215 (1988-08-01), Abou-Gharbia
patent: 4843074 (1989-06-01), Rzeszotarski
Chem. Abstr., 57 9805c (1962).
Richardson, B. P. et al., Nature, 316, 126-131 (1985).
Daus Donald G.
John Wyeth and Brother Limited
Seifert Arthur G.
LandOfFree
Pyrazinyl and pyridazinyl ethers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pyrazinyl and pyridazinyl ethers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazinyl and pyridazinyl ethers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-115806