Pyrazinone, pyridinone, piperidine and pyrrolidine thrombin inhi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

5142358, 514255, 514326, 514341, 514342, 514343, 514370, 514392, 514400, 544120, 544131, 544132, 544405, 544406, 544407, 546208, 5462727, 5462751, 548195, 5483381, 5483315, 548204, A61K 31415, A61K 31495, C07D40312

Patent

active

059326069

ABSTRACT:
A compound which inhibits human thrombin and where has the structure and pharmaceutically acceptable salts thereof, wherein such as ##STR1## which are useful for inhibiting formation of blood platelet aggregates in blood in a mammal.

REFERENCES:
patent: 5260307 (1993-11-01), Ackermann et al.
patent: 5405854 (1995-04-01), Ackermann et al.
patent: 5510369 (1996-04-01), Lumma et al.

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