Pyrazine diazohydroxide compositions and method of use as cytost

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31495

Patent

active

048451010

ABSTRACT:
Chemical compounds are provided including pyrazine diazohydroxides (I), as well as methods for their production, pharmaceutical compositions comprising the compounds, and methods of treatment using the compounds in dosage form. Compounds of the invention have pharmacological properties and are useful cytostatic agents and cell growth inhibiting agents. ##STR1##

REFERENCES:
Baker et al., Anti-Cancer Drug Design (1987), 2, 297-309, "Synthesis, Chemical Stability and Pre-Clinical Anti-Tumor Activity of Pyrazine Diazohydroxide, Sodium Salt (NSC-361456)".
Hirschberg et al., J. Org. Chem. 1961, 26, 1907-1912.
Bunton et al., J.A.C.B. 1974, pp. 3267-3275.
Ota et al., Chem. Abst., vol 94 (1981) 120619w.
Sogo Yakuko Co. Ltd. Chem. Abst., vol. 97 (1982) 182417z.
Watanabe et al., Chem. Abst., vol. 100 (1984) 34467f.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pyrazine diazohydroxide compositions and method of use as cytost does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrazine diazohydroxide compositions and method of use as cytost, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazine diazohydroxide compositions and method of use as cytost will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-852662

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.