Pyrazine compounds as phosphodiesterase 10 inhibitors

Details Pyrazine compounds as phosphodiesterase 10 inhibitors Pyrazine compounds as phosphodiesterase 10 inhibitors

2009-11-16

2011-11-08

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S408000, C546S245000, C548S309400

Reexamination Certificate

active

08053438

ABSTRACT:
Pyrazine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.

REFERENCES:
patent: 4198417 (1980-04-01), Ong et al.
patent: 7470702 (2008-12-01), Staehle et al.
patent: 2006/0281762 (2006-12-01), Staehle et al.
patent: 2007/0021456 (2007-01-01), Mitjans et al.
patent: 2008/0194605 (2008-08-01), Heinrich et al.
patent: 2009/0082404 (2009-03-01), Staehle et al.
patent: WO 2004/087155 (2004-10-01), None
patent: WO 2005/019216 (2005-03-01), None
patent: WO 2005/037829 (2005-04-01), None
patent: WO 2005/042520 (2005-05-01), None
patent: WO 2005/070920 (2005-08-01), None
patent: WO 2007/016228 (2007-02-01), None
patent: WO 2007/098169 (2007-08-01), None
patent: WO 2007/100646 (2007-09-01), None
patent: WO 2007/129183 (2007-11-01), None
patent: WO 2008/057280 (2008-05-01), None
patent: WO 2008/084299 (2008-07-01), None
patent: WO 2009/081259 (2009-07-01), None
patent: WO 2010/008739 (2010-01-01), None
Dounay et al., “Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists,” Bioorganic & Medicinal Chemistry Letters, 2010, 20(3):1114-1117.
Villani et al., “Benzopyranopyridine Derivatives. 1. Aminoalkyl Derivatives of the Azaxanthenes as Bronchodilating Agents,” Journal of Medicinal Chemistry, 1975, 18(1):1-8.

Affiliated with

Also associated with

Rating

Pyrazine compounds as phosphodiesterase 10 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrazine compounds as phosphodiesterase 10 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazine compounds as phosphodiesterase 10 inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4289934