Pyrazine-based tubulin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S336000, C546S268100

Reexamination Certificate

active

08084456

ABSTRACT:
A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating a hyperproliferation-related disease state or disorder in a subject using a compound of formula (I) is also described.

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Ding et al., J. Am. Chem. Soc. (2002) 124(8):1594-1596.
International Search Report for PCT/AU2003/001661, mailed on Mar. 11, 2004, 2 pages.

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